Struggling with Chronic Back Pain Radiating into Your Leg(s)?
You may be eligible to join a clinical trial exploring a new plant-based investigational medication - trial-related care at no cost to you.
- Condition: chronic back pain
- Clinical Trial Type: Clinical Trial

Have you been living with persistent low back pain that radiates or shoots down into your leg(s), below the knee, for more than six months – and pain medication does not give you lasting relief? You may be eligible for a clinical trial exploring an investigational medication for chronic Painful Lumbosacral Radiculopathy (PLSR), described by doctors also as sciatica.
Who Can Join?
You may be eligible if you:
are a U.S. resident, age18 or older
have experienced pain starting in your lower back and radiating into one or both legs, below the knee, for more than six months
have leg pain at least as intense as your back pain and, present even at rest, not only when walking
have not found lasting relief with standard pain medications
are not currently pregnant or breastfeeding
do not have severe physical or mental health conditions
Why Participate?
No Cost for Trial-Related Care
You will not be charged for trial-related exams, procedures, and medications.
Compensation for Your Time and Effort
You will be reimbursed for your time and travel expenses.
Contribute to the Future of Pain Relief
Your participation may help researchers better understand PLSR and inform future treatment options.
What is This Clinical Trial About?
PLSR is a form of chronic pain that starts in your lower back and radiates down into one or both legs, often below the knee. For this trial, the leg pain must be at least as intense as the back pain and must be present even at rest, not only when walking.
It is a common condition that affects millions worldwide and, for many, finding an effective treatment can be a long and challenging journey. This clinical trial is looking at the effects of a plant-based investigational medication in participants with PLSR.
What Does Participation Involve?
Are There Any Risks?
Ready to Take the First Step?
Fill out the form below. A member of the trial team will contact you to discuss your eligibility and guide you through the next steps.
🔒 We understand the importance of privacy. All data will be kept confidential and used solely for the purposes of this clinical trial in accordance with our Data Protection Information document. Please see our Data Protection Information document for more information.
🛡 This clinical trial complies with all FDA regulations and has been reviewed by an independent Institutional Review Board (IRB).
🌎 This trial is available for U.S. residents only. If you are not a U.S. resident, do not provide us with any information and do not fill out the contact form.
Participating sites
Find a clinical trial site near you
This clinical trial is running at several locations. Enter your city or use your current location and we'll show you the site closest to you.
Austin
Central Texas Clinical Research, LLC
Bradenton
Bradenton Research Center
Charleston
Clinitiative - Clinical Trials of South Carolina - Charleston
Cleveland
Velocity Clinical Research - Cleveland
Evergreen
Starlight Clinical Research
Friendswood
Innovare Research Group I
Hialeah
AGA Clinical Trials
Houston
HD Research - Memorial Hermann Village
Jacksonville
Green Leaf Clinical Trials
Katy
R & H Clinical Research
Knoxville
Alliance for Multispecialty Research - Knoxville
Lewisville
Epic Clinical Research - Lewisville
Long Beach
Central Medical Research Institute
Longmont
Tekton Research - Longmont
Maitland
K2 Medical Research - Maitland II
Medford
Velocity Clinical Research - Medford
Miami
Floridian Research Institute LLC I
Miami
Alma Clinical Research
Mobile
AMR Mobile
Monroe
Monroe Biomedical Research - Monroe
Ohama
QCR Network
Orlando
Conquest Research - Lake Nona
Pembroke Pines
Alfa Medical Research - Pembroke Pines
Port Orange
United Medical Research
Provo
Boeson Research
Salt Lake City
CenExel JBR - Salt Lake City
Suffolk
Velocity Clinical Research - Suffolk
Tempe
Alliance for Multispecialty Research - Tempe I
Wichita
Alliance for Multispecialty Research - Wichita East
Wichita Falls
Grayline Research Center
Winston-Salem
Progressive Medicine of the Triad, LLC
Winter Park
Conquest Research - Winter Park