Struggling with Chronic Back Pain Radiating into Your Leg(s)?

You may be eligible to join a clinical trial exploring a new plant-based investigational medication - trial-related care at no cost to you.

  • Condition: chronic back pain
  • Clinical Trial Type: Clinical Trial

Have you been living with persistent low back pain that radiates or shoots down into your leg(s), below the knee, for more than six months – and pain medication does not give you lasting relief? You may be eligible for a clinical trial exploring an investigational medication for chronic Painful Lumbosacral Radiculopathy (PLSR), described by doctors also as sciatica.

Who Can Join?

You may be eligible if you:

  • are a U.S. resident, age18 or older

  • have experienced pain starting in your lower back and radiating into one or both legs, below the knee, for more than six months

  • have leg pain at least as intense as your back pain and, present even at rest, not only when walking

  • have not found lasting relief with standard pain medications

  • are not currently pregnant or breastfeeding

  • do not have severe physical or mental health conditions

Why Participate?

No Cost for Trial-Related Care
You will not be charged for trial-related exams, procedures, and medications.

Compensation for Your Time and Effort
You will be reimbursed for your time and travel expenses.

Contribute to the Future of Pain Relief
Your participation may help researchers better understand PLSR and inform future treatment options.

What is This Clinical Trial About?

PLSR is a form of chronic pain that starts in your lower back and radiates down into one or both legs, often below the knee. For this trial, the leg pain must be at least as intense as the back pain and must be present even at rest, not only when walking.

It is a common condition that affects millions worldwide and, for many, finding an effective treatment can be a long and challenging journey. This clinical trial is looking at the effects of a plant-based investigational medication in participants with PLSR.

What Does Participation Involve?

Are There Any Risks?

Ready to Take the First Step?

Fill out the form below. A member of the trial team will contact you to discuss your eligibility and guide you through the next steps.

🔒 We understand the importance of privacy. All data will be kept confidential and used solely for the purposes of this clinical trial in accordance with our Data Protection Information document. Please see our Data Protection Information document for more information.

🛡 This clinical trial complies with all FDA regulations and has been reviewed by an independent Institutional Review Board (IRB).

🌎 This trial is available for U.S. residents only. If you are not a U.S. resident, do not provide us with any information and do not fill out the contact form.

Participating sites

Find a clinical trial site near you

This clinical trial is running at several locations. Enter your city or use your current location and we'll show you the site closest to you.

Austin

Central Texas Clinical Research, LLC

900 E 30th St #302 Austin, TX 78705
Register here

Bradenton

Bradenton Research Center

3924 9th Ave W, Bradenton, FL 34205
Register here

Charleston

Clinitiative - Clinical Trials of South Carolina - Charleston

2695 Elms Plantation Blvd Ste D Charleston, SC 29406
Register here

Cleveland

Velocity Clinical Research - Cleveland

3619 Park E Dr, Suite 300, Beachwood, OH 44122
Register here

Evergreen

Starlight Clinical Research

27905 Meadow Drive #516 Evergreen, CO 80439
Register here

Friendswood

Innovare Research Group I

1305 W Parkwood Ave, Friendswood, Suite A-107, TX 77546
Register here

Hialeah

AGA Clinical Trials

4980 W 10th Ave Ste 101, Hialeah, FL 33012
Register here

Houston

HD Research - Memorial Hermann Village

1120 Business Center Dr #110, Houston, TX 77043
Register here

Jacksonville

Green Leaf Clinical Trials

6100 Greenland Rd, Ste 702, Suite 905, Jacksonville, FL 32258
Register here

Katy

R & H Clinical Research

23215 Red River Dr, Katy, TX 77494
Register here

Knoxville

Alliance for Multispecialty Research - Knoxville

1924 Alcoa Hwy Suite 107 4th & 5th Floors North Tower
Register here

Lewisville

Epic Clinical Research - Lewisville

500 W Main St, Ste 320, Lewisville, TX 75057
Register here

Long Beach

Central Medical Research Institute

235 East Broadway, Suite 940, Long Beach, California 90802
Register here

Longmont

Tekton Research - Longmont

205 S Main St, Suite A2, Longmont, CO 80501
Register here

Maitland

K2 Medical Research - Maitland II

101 Southhall Lane Suite 150 (Clinic), Suite 410 (Pharmacy)
Register here

Medford

Velocity Clinical Research - Medford

3121 Signature Court
Register here

Miami

Floridian Research Institute LLC I

1021 Ives Dairy Rd #214, Miami, FL 33179
Register here

Miami

Alma Clinical Research

14140 SW 8th St, Miami, FL 33184
Register here

Mobile

AMR Mobile

100 Memorial Hospital Dr, Mobile, AL 36608
Register here

Monroe

Monroe Biomedical Research - Monroe

343 Venus St, Monroe, NC 28112
Register here

Ohama

QCR Network

10040 Regency Circle, Suite 375
Register here

Orlando

Conquest Research - Lake Nona

13567 Narcoossee Rd, Orlando, FL 32832
Register here

Pembroke Pines

Alfa Medical Research - Pembroke Pines

17894 NW 2nd St, Pembroke Pines, FL 33029
Register here

Port Orange

United Medical Research

5111 S Ridgewood Ave Ste 101 & 301, Port Orange, FL 32127
Register here

Provo

Boeson Research

1055 N 300 W Ste 308 Building 8, Provo, UT 84604
Register here

Salt Lake City

CenExel JBR - Salt Lake City

650 E 4500 S STE 100
Register here

Suffolk

Velocity Clinical Research - Suffolk

7007 Harbour View Blvd Ste 109, Suffolk, VA 23435
Register here

Tempe

Alliance for Multispecialty Research - Tempe I

1492 S Mill Ave, Ste 312
Register here

Wichita

Alliance for Multispecialty Research - Wichita East

8110 E 32nd St N Ste 250, Wichita, KS 67226
Register here

Wichita Falls

Grayline Research Center

3300 Seymour Hwy, Wichita Falls, TX 76309
Register here

Winston-Salem

Progressive Medicine of the Triad, LLC

2825 Lyndhurst Ave #105, Winston-Salem, NC 27103
Register here

Winter Park

Conquest Research - Winter Park

2233 Lee Rd Ste 101, Winter Park, FL 32789
Register here